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Naslov Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study (Article)
Autori Mitrovic Jelena R  Bjelosevic-Ziberna Maja  Vukadinovic Aleksandar A  Knutson Daniel E  Sharmin Dishary  Kremenovic Aleksandar S  Grabnar Pegi Ahlin  Planinsekb Odon  Lunter Dominique Jasmin  Cook James M  Savic Miroslav M  Savic Snezana D 
Info EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, (2023), vol. 189 br. , str. -
Projekat Science Fund of the Republic of Serbia [7749108]; National Institutes of Health, USA [R01 NS076517, R01 MH096463]; National Science Foundation, Division of Chemistry [CHE-1625735]
Ispravka ISI/Web of Science   Članak   Elečas   Rang časopisa  
Naslov High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances (Article)
Autori Mitrovic Jelena R  Divovic-Matovic Branka  Knutson Daniel E  Petkovic Milos R  Djorovic Djordje J  Randjelovic Danijela V  Dobricic Vladimir D  Djokovic Jelena B  Lunter Dominique Jasmin  Cook James M  Savic Miroslav M  Savic Snezana D 
Info INTERNATIONAL JOURNAL OF PHARMACEUTICS, (2023), vol. 633 br. , str. -
Projekat Science Fund of the Republic of Serbia [7749108]; Ministry of Education, Science and Technological Development, Republic of Serbia [451-03-68/2022-14/200161]; NIH [R01NS076517, 451-03-68/2022-14/200026]; project Neuroimmune aspects of mood, anxiety and cognitive effects of leads/drug candidates acting at GABAA and/or sigma-2 receptors: In vitro/in vivo delineation by nano-and hiPSC-based platforms-NanoCellEmoCog; University of Belgrade - Institute of Chemistry, Technology and Metallurgy; [DA-043204]
Ispravka ISI/Web of Science   Članak   Elečas   Rang časopisa   Citati:
Naslov Behavioural interaction of pyrazoloquinolinone positive allosteric modulators at alpha 6GABA(A) receptors and diazepam in rats: Anti-diazepam-induced ataxia action as a structure-dependent feature (Article)
Autori Divovic-Matovic Branka  Knutson Daniel E  Mitrovic Jelena R  Stevanovic Vladimir  Stanojevic Boban R  Savic Snezana D  Cook James M  Savic Miroslav M 
Info BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, (2022), vol. 131 br. 6, str. 514-524
Projekat Science Fund of the Republic Serbia [7749108]; Ministry of Education, Science and Technological Development, Republic of Serbia [451-03-68/2022-14/200161]; NIH [DA-043204, R01NS076517]
Ispravka ISI/Web of Science   Članak   Elečas   Rang časopisa   Citati: ISI/Web of Science  
Naslov Positive modulation of alpha 5GABAA receptors leads to dichotomous effects in rats on memory pattern and GABRA5 expression in prefrontal cortex and hippocampus (Article)
Autori Santrac Anja  Batinic Bojan A  Timic-Stamenic Tamara S  Arandjelovic Jovana  Sharmin Dishary  Knutson Daniel E  Cook James M  Savic Miroslav M 
Info BEHAVIOURAL BRAIN RESEARCH, (2022), vol. 416 br. , str. -
Projekat Ministry of Education, Science and Technological Development, Republic of Serbia; University of Belgrade-Faculty of Pharmacy [451-03-9/2021-14/200161]; National Institutes of Health (NIH) - USA [DA-043
Ispravka ISI/Web of Science   Članak   Elečas   Rang časopisa   Citati: ISI/Web of Science  
Naslov Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach (Article)
Autori Mitrovic Jelena R  Divovic-Matovic Branka  Knutson Daniel E  Djokovic Jelena B  Kremenovic Aleksandar S  Dobricic Vladimir D  Randjelovic Danijela V  Pantelic Ivana  Cook James M  Savic Miroslav M  Savic Snezana D 
Info PHARMACEUTICS, (2021), vol. 13 br. 8, str. -
Projekat Ministry of Education, Science and Technological Development, Republic of Serbia [451-03-9/2021-14/200161, 451-03-09/2021-14/200126, 451-03-9/2021-14/200026]; National In
Ispravka ISI/Web of Science   Članak   Elečas   Rang časopisa   Citati: ISI/Web of Science   Scopus  
Naslov Nanocrystal dispersion of DK-I-56-1, a poorly soluble pyrazoloquinolinone positive modulator of alpha 6 GABAA receptors: Formulation approach toward improved in vivo performance (Article)
Autori Mitrovic Jelena R  Divovic Branka  Knutson Daniel E  Djokovic Jelena B  Vulic Predrag J  Randjelovic Danijela V  Dobricic Vladimir D  Calija Bojan R  Cook James M  Savic Miroslav M  Savic Snezana D 
Info EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, (2020), vol. 152 br. , str. -
Projekat Ministry of Education, Science and Technological Development of the Republic of Serbia [TR34031, OI175076]; National Institutes of Health (NIH) - USA [R01 NS076517, R01 M
Ispravka ISI/Web of Science   Članak   Elečas   Rang časopisa   Citati: ISI/Web of Science  
Naslov Combatting the opioid and benzodiazepine epidemic by the synthesis of novel safer drugs designed to be functionally selective for alpha 5-or alpha 6-containing GABAA receptors (Meeting Abstract)
Autori Knutson Daniel E  Li Guanguan  Prevot Thomas  Arnold Leggy  Chiou Lih-Chu  Ernst Margot  Mihovilovic Marko  Savic Miroslav M  Sieghart Werner  Sibille Etienne  Cook James M 
Info ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, (2019), vol. 258 br. , str. -
Ispravka ISI/Web of Science   Elečas   Citati: ISI/Web of Science  
Naslov Nanosuspension formulation of DK-I-56-1, a deuterated ligand functionally selective for the alpha 6 GABAA receptors, induces hyperlocomotion in mice (Meeting Abstract)
Autori Divovic-Matovic Branka  Mitrovic Jelena R  Knutson Daniel E  Batinic Bojan A  Savic Snezana D  Cook James M  Savic Miroslav M 
Info EUROPEAN NEUROPSYCHOPHARMACOLOGY, (2019), vol. 29 br. , Suppl. 6, str. S327-S328
Ispravka ISI/Web of Science   Članak   Elečas   Rang časopisa   Citati: ISI/Web of Science  
Naslov Treatment of sensorimotor gating deficits in neuropsychiatric disorders using deuterated alpha 6-GABAAR subtype selective ligands (Meeting Abstract)
Autori Knutson Daniel E  Kodali Revathi  Treven Marco  Divovic Branka  Lee Hsin-Jung  Chou Jui-Feng  Chen Hon-Lie  Chiou Lih-Chu  Ernst Margot  Mihovilovic Marko  Savic Miroslav M  Sieghart Werner  Cook James M 
Info ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, (2019), vol. 257 br. , str. -
Ispravka ISI/Web of Science   Elečas   Citati: ISI/Web of Science  
Naslov Trigeminal neuropathic pain development and maintenance in rats are suppressed by a positive modulator of alpha 6 GABA(A) receptors (Article)
Autori Vasovic Dina D  Divovic Branka  Treven Marco  Knutson Daniel E  Steudle Friederike  Scholze Petra  Obradovic Aleksandar Lj  Fabjan Jure  Brkovic Bozidar B  Sieghart Werner  Ernst Margot  Cook James M  Savic Miroslav M 
Info EUROPEAN JOURNAL OF PAIN, (2019), vol. 23 br. 5, str. 973-984
Projekat Ministry of Education, Science and Technological Development, R. Serbia-Grant [175,076]; FWF [I2306]; National Institutes of Health [MH096463, NS076517]; Milwaukee Institute for Drug Discovery; University of Wisconsin-Milwaukee's Shimadzu Laboratory for A
Ispravka ISI/Web of Science   Članak   Elečas   Rang časopisa   Citati: ISI/Web of Science   Scopus  
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